We report a case of nodular fasciitis (NF) of the breast, which was cytologically diagnosed as a spindle cell proliferation with undetermined malignant potential. Owing to small size of the lesion (5.9 × 3.7 × 4.1 mm), only fine needle aspiration (FNA) cytology was performed under ultrasound guidance Nodular fasciitis Comment: This is spindle stellate cell neoplasm arranged in short bundles and fascicles. The nuclei are ovoid and monomorphic, with occasional mitotic activity. The stroma is variably myxoid to collagenous, with scattered lymphocytes and extravasated erythrocytes Nodular fasciitis is a rapidly growing lesion of benignfibroblastic tissue that most commonly is diagnosed in youngand middle aged adults, with a peak incidence in the thirdand fourth decades of life. The most common presentation i Nodular fasciitis (NF) is a benign, self-limited fibroblast ic/myofibroblastic proliferation most commonly occur-ring in the upper extremities (volar aspect of the forear m),trunk,andbackinadults.However,numerousaddi- FNA cytology specimens of masses confirmed to be NF by excision or clinical follow-up. Data Collectio Nodular fasciitis (NF) is a benign, self-limited, fibroblastic/myofibroblastic proliferation that is diagnostically challenging, often mimicking a malignant process due to its rapid growth clinically and its high cellularity, mitotic activity, and variable/nonspecific cytomorphologic findings
Home » Courses » Paediatric Cytology (Recently updated) » MIXOID LESIONS » Nodular fasciitis. Toggle navigation. Paediatric Cytology (Recently updated) Course objectives. Content. INTRODUCTION; I - RENAL NEOPLASMS; Nodular fasciitis. For more details see spindle cell lesions. Nodular fasciitis histology Histology refers to the particular kinds of cells in a tumor. These can be seen by looking at tumor tissue under a microscope. Malignant tumors and nodular fasciitis.. FNA cytology is an important tool in the diagnosis of nodular fasciitis, in appropriate clinico-radiological setting. AB - Background and Objective: Nodular fasciitis (NF) is a self-limiting, transient neoplasm composed of fibroblasts and myofibroblasts Nodular fasciitis presents as a rapidly growing soft tissue mass which may follow a history of trauma. Histology of nodular fasciitis Low power examination of nodular fasciitis shows a well- circumscribed discrete mass in the subcutaneous adipose tissue (figure 1). Dermal and intravascular forms have also been described
A case of nodular fasciitis involving the thumb of a 4-year-old male child is presented. Main significance lies in clinical and pathological recognition of the lesion to avoid over-treatment. Nodular fasciitis remains a difficult diagnosis by fine needle aspiration cytology, particularly when it occurs in locations such as the hand Nodular fasciitis of the breast is rarely diagnosed on cytology alone and a histological diagnosis is usually required for a definitive diagnosis. However, in this case, the lesion spontaneously resolved prior to core biopsy or diagnostic open biopsy Papillary thyroid carcinoma with nodular fasciitis-like stroma is one of the rare variants of papillary thyroid carcinoma. The problems posed by the exuberant nodular fasciitis-like stroma, which obscures the neoplastic nature of the tumor, are recognized in surgical pathology but have received little attention in the cytopathology literature
Nodular fasciitis is a benign tumour that arises from the proliferation of fibroblasts and myofibroblasts. It most commonly arises from the extremities and trunk and rarely from the head and neck region .Despite its benign nature, it characteristically exhibits rapid growth, which is demonstrated on histology or cytology as increased mitotic activity Nodular fasciitis (NF) is a benign reactive or inflammatory condition of mesenchymal fibroblasts. Rapid growth and histological features make nodular fasciitis a mimicker of malignancies such as sarcomas, however, nodular fasciitis is a benign lesion and does not metastasize Nodular fasciitis of parotid region: A pitfall in the diagnosis of pleomorphic adenomas on fine‐needle aspiration cytology Reda S. Saad M.D., Ph.D. Corresponding Autho
Reda S. Saad, Hidehiro Takei, Jane Lipscomb, Bernardo Ruiz, Nodular fasciitis of parotid region: A pitfall in the diagnosis of pleomorphic adenomas on fine‐needle aspiration cytology, Diagnostic Cytopathology, 10.1002/dc.20323, 33, 3, (191-194), (2005) We report a case of nodular fasciitis of the breast in a 48-year-old woman who presented with a tender rapidly growing right breast lump. Ultrasound guided fine needle aspiration (FNA) of the solid mass was performed. Cytology was reported as atypical spindle cell neoplasm and the patient was referred to a breast surgeon at a tertiary institution for a definitive diagnosis and further management Cytopathology, often called cytology, is the study of pathologic changes in cells.. Specimen types include exfoliated cervical cytology (Pap tests), urine, body cavity fluids (pleural, pericardial, and peritoneal), cerebrospinal fluid, and fine needle aspirations from any body site, among others (see detail articles section).These are often collected by minimally invasive means In addition, once the diagnosis of nodular fasciitis (NF) is made, even though known as benign, the most frequent treatment for this condition is still surgery. What we intend to show is that fine needle aspiration cytology (FNAC) is a minimally invasive technique that can make the diagnosis and offer a watchful waiting strategy
1/2. Fig 29 - Nodular fasciitis- Myxoid spindle cell lesion. Hypercellular smear. Recognition of a myxoid spindle cell lesion in 5% of the cases. Dispersed to cohesive cells. Bland looking, but pleomorphic myofibroblasts (plump, spindle, ovoid, kidney-shaped nuclei) Binucleated forms. Triangular cells. Eccentrically placed nuclei with bland. Nodular fasciitis: a case with unusual clinical presentation initially diagnosed by aspiration cytology. Fernando SS(1), Gune S, George S, Van Gelderen P. Author information: (1)Department of Anatomical Pathology, South Western Area Pathology Services, Liverpool, NSW, Australia Nodular fasciitis, Fine needle aspiration cytology, Pleomorphic adenoma INTRODUCTION Nodular fasciitis is a benign, idiopathic, reactive proliferation of myofibroblasts, which typically presents as a solitary, rapidly enlarging nodule. First reported in 1955 by Konwaller et al,1 who named it pseudo-sarcomatous fasciitis because i Nodular fasciitis (NF), proliferative fasciitis (PF) and proliferative myositis (PM) are reactive lesions that typically resolve spontaneously.  The clinical course is completely benign, but the high risk of misinterpreting these lesions as malignant owing to its rapid growth, high cellularity and high mitotic activity on histology has been.
Nodular fasciitis of parotid region: a pitfall in the diagnosis of pleomorphic adenomas on fine-needle aspiration cytology. Saad RS , Takei H , Lipscomb J , Ruiz B Diagn Cytopathol , 33(3):191-194, 01 Sep 200 Nodular fasciitis is rarely diagnosed by fine needle aspiration cytology or core needle biopsy, and it usually requires excisional biopsy for histologic confirmation. While authors have reported the proliferation of neoplastic spindle cells was suspected, no definitive diagnosis was obtained with aspiration cytology [ 8 ] Introduction. Nodular fasciitis, described for the first time in 1955 by Konwaler et al. , is a benign disorder characterized by a pseudoneoplastic proliferation of myofibroblasts.Generally, it is detected in the soft tissue of the extremities, of the trunk and the neck, although involvement of muscles, fasciae and parenchymatous organs was described, and virtually all parts of the body can.
Cellular stroma with new bone, atypia and mitotic figures, rarely cartilage; zonation often present, although zones may be poorly demarcated Early lesions (3 weeks): inner cellular zone resembling nodular fasciitis with short fascicles or haphazard fibroblasts that are uniform with faint eosinophilic cytoplasm, tapering processes, vesicular or finely granular nuclei and variable nucleoli. Nowadays, histopathology and immunohistochemistry play a pivotal role in diagnosis as fine-needle aspiration cytology (FNAC) can be correctly diagnosed only if the cytologist is aware of its clinical and cytologic features. Following a short Literature review, the authors report a rare case of maxillary nodular fasciitis in an 85-year-old.
A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) &.. Nodular fasciitis (NF), proliferative fasciitis (PF), and proliferative myositis (PM) are pseudosarcomatous lesions that typically resolve spontaneously. We previously reported the feasibility of diagnosing this family of lesions by fine-needle aspiration cytology (FNAC) based on 17 cases . I-RENAL NEOPLASMS. Congenital mesoblastic nephroma. Nephroblastoma (Wilms' tumour) Rhabdoid tumour. Clear cell sarcomaRenal primitive neuroectodermal tumour. Renal cell carcinoma. Metanephric adenoma. II-RHABDOMYOSARCOMA
Nodular fasciitis is a benign reactive proliferation that usually involves the deep fascia. The rapidly growing, the abundant cellularity, and the mitotic activity noted on histology can simulate an aggressive entity, such as sarcoma. We report an uncommon case of nodular fasciitis involved the chest wall of a thirteen boy and its management, emphasizing the need to consider this lesion in the. Nodular fasciitis, also called pseudosarcomatous fasciitis, proliferative fasciitis or infiltrative fasciitis, is a rare, noncancerous tumor. It appears in soft tissue anywhere in the body. Nodular occurs mostly in adults aged between 20 to 40, and it affects males and females with equal frequency Nodular fasciitis (NF) is a rapidly growing benign lesion rarely reported in the parotid gland. It shares cytological features with other benign and malignant parotid neoplasms and may be difficult to diagnose based on fine needle aspiration cytology alone. Given this diagnostic conundrum, surgical excision for histology is recommended to facilitate definitive diagnosis Click here for a list of all centers ; Clinical Departments . Anesthesiology ; Emergency Medicine ; Family and Community Medicin
Fine needle aspiration cytology of nodular fasciitis presenting as a mass in the male breast: report of an unusual case. Paker I, Kokenek TD, Kacar A, Ceyhan K, Alper M. Cytopathology, 24(3):201-203, 09 Jan 2012 Cited by: 6 articles | PMID: 2223003 Nodular fasciitis. Nodular fasciitis also known as pseudosarcomatous fasciitis, infiltrative fasciitis, proliferative fasciitis or subcutaneous pseudosarcomatous fibromatosis, is a rapidly growing benign soft tissue tumor of fibroblastic or myofibroblastic proliferation that is frequently located in the deep subcutaneous tissue or in the fascia 1) Nodular fasciitis is a benign reactive proliferative lesion of fibroblast cells, which can occur throughout the body. However, it has rarely been reported in the breast of an elderly woman. Our patient was an 88-year-old Asian woman who had noticed a mass in her right breast for 1 month before presentation to our hospital. The mass was elastic-hard and 20 mm in size
Background: Nodular fasciitis (NF) is a clonal, self-limited proliferation that has only rarely been described in the parotid gland. Because of its potential to mimic benign and malignant parotid neoplasms clinically, radiographically, and cytomorphologically, NF is often managed with unnecessary surgery, which is associated with a risk for significant surgical complications . Fine-needle aspiration biopsy (FNAB) is a minimally invasive, rapid, accurate method of obtaining diagnostic material from head and neck masses In 24 case reports of nodular fasciitis of the breast, four underwent FNA.1 -791730 A speciﬁc diagnosis of nodular fasci-itis was not made in any of these. Six underwent subsequent core biopsy with a deﬁnitive diagnosis of nodular fasciitis in three based on a combination of histological ﬁndings and spon-taneous regression of the lesion
nodular fasciitis in the literature, there has been no discussion of the difﬁculty in diagnosing nodular fas-ciitis pre-operatively.4-7The purpose of this study is to report the clinical, radiological, cytological and intra-operative ﬁndings made prior to the determi-nation of nodular fasciitis on ﬁnal histopathological analysis Background: Nodular fasciitis is a benign disease characterized by reactive fibroblast proliferation and is also called pseudosarcomatous fibromatosis.Differentiation of nodular fasciitis from sarcoma is difficult. We report a rare case of estrogen receptor (ER)-positive nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology (FNAC) Nodular fasciitis or pseudosarcomatous fasciitis is a group of reactive lesions in the superficial or deep fascia resembling a variety of benign and malignant soft tissue tumors of the vulva [1,2]. Though its most common occurrence is in the subcutaneous tissue of the extremities and trunk, vulvar nodular fasciitis is rare and only 14 cases to. Nodular Fasciitis Elizabeth A. Montgomery, MD Key Facts Clinical Issues Age: 3rd-4th decades Gender: M = F Most lesions are benign and do not recur, even if incompletely excised Simple excision is treatment Microscopic Pathology Loose storiform, feathery pattern with tissue culture appearance, variable myxoid stroma, cystic spaces, strands of keloid-like collagen Mitoses present bu The 2 most important differentials in cytology are fibromatosis and sarcomas, both which are deep to the subcutis, unlike most cases of nodular fasciitis. Cells from nodular fasciitis do not have significant cytologic atypia like marked pleomorphism, hyperchromasia o
Nodular fasciitis (NF), very uncommon in the parotid gland, is a benign myofibroblastic proliferation that may be mistaken for other neoplastic proliferations. The mass-like clinical presentation and histologic features result in frequent misclassification, resulting in inappropriate clinical management. There are only a few reported cases in the English literature. Cases within the files of. Nodular fasciitis has propensity to occur in children and young adults on head and neck, trunk and upper extremities, but it is extremely rare to occur in the auricular region. Its etiology was thought to be reactive, but it is now found to have USP6-MYH9 fusion gene in most cases, thus favoring a neoplastic process . Males and females are equally affected. It usually presents as a rapidly growing soft tissue mass, somewhat tender and fixed to the subjacent structures, but with freely moveable overlying skin
Nodular fasciitis is a benign reactive process that mimics malignant tumors clinically, in imaging studies and on fine-needle aspiration cytology. To our knowledge, nodular fasciitis has no previously known association with dermatofibrosarcoma protuberans Fasciitis; Nodular; Adenoma; Pleomorphic. abstract. Nodular fasciitis is a rare benign lesion. Here we report a case of post-auricular nodular fasciitis, which was misdiagnosed by fine-needle aspiration cytology (FNAC) as pleomorphic adenoma. An 18-year-old male presented at Al-Nahdha Hospital, physical examination revealed a right post aural. , Some reactive and benign lesions (such as nodular fasciitis, schwannoma, fibrous, and myxoid tumors) may contain atypical cells. Differentiation of such reactive/benign tumor from low-grade STTs is a challenging issue solely on the basis of cytology Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): https://doi.org/10.4103/0970-9... (external link
Papillary thyroid carcinoma with nodular fasciitis-like stroma. Pitfalls in fine-needle aspiration cytology. Arch Pathol Lab Med. 1999;123:838. CAS PubMed Google Scholar 5. Basu S, Nair N, Shet T, et al. Papillary thyroid carcinoma with exuberant nodular fasciitis-like stroma: treatment outcome and prognosis Nodular fasciitis of the external ear masquerading as pleomorphic adenoma: A potential diagnostic pitfall in fine needle aspiration cytology . By Jain Deepali, Khurana Nita and Jain Shyama. Abstract Background: Nodular fasciitis (NF) is a benign myofibroblastic proliferation in soft tissue. The most common sites are extremities, followed. Mokbel KM, Benson JR, Fisher C, Baum M, Nodular fasciitis- Part II: A rare cause of a lump in the breast in a 44 year old woman. The Breast 3, pp 48-49, 1994. Article Google Scholar 12) Maly B, Maly A: Nodular fasciitis of the breast: report of a case initially diagnosed by fine needle aspiration cytology
Pre-operative suspicion of nodular fasciitis may arise based on a benign clinical course, history of trauma and cytological findings, and on the above-mentioned imaging signs. However, definitive diagnosis of nodular fasciitis depends on histopathological analysis Nodular fasciitis Typical clinical presentation; Highly characteristic metachromatic myxoid stroma; Cells loosely and haphazardly arranged in fragments; Fibromatosis Less cellularity than fibrosarcoma; Bland spindle nuclei; Inconspicuous nucleoli; Absence of mitosis; Embryonal Rhabdomyosarcoma Myxoid stroma; Desmin: Positive; Myo-D1: Positiv Keywords: Nodular fasciitis, Breast, Benign, Elderly woman, Immunostaining Background Although nodular fasciitis (NF) of the breast appears ma-lignant on clinical and diagnostic imaging studies, it is dif-ficult to diagnose by cytology or needle biopsy, as well as to treat. NF rarely occurs in the breast and is, furthermore
Nodular fasciitis (NF), proliferative fasciitis (PF), and proliferative myositis (PM) are pseudosarcomatous lesions that typically resolve spontaneously. We previously reported the feasibility of diagnosing this family of lesions by fine-needle aspiration cytology (FNAC) based on 17 cases. The present study includ Although this low-power appearance may superficially resemble that of PF/PM, the c-FOS-positive cells in nodular fasciitis do not possess large epithelioid cytology, and the staining is.
Cytology reveals cells with one or more cytoplasmic fat vacuoles which push aside and indent the nuclei in the center. Do Nodular Fasciitis and Myositis Ossificans develop following trauma? Nodular Fasciitis. Exhibits zonal growth with hypocellular center and hypercellular periphery in a myxoid matrix of spindle cell proliferation. Nodular. Nodular fasciitis ke hlahala e se nang mofetše e etsisang mofets'e. E ka hlaha ka lisele tse bonolo kae kapa kae 'meleng. Le ha ho le bohlokoa ho fumana tlhahlobo e hlakileng ho netefatsa hore hlahala ea hau ha e na mofetše, fasciitis ea nodular e phekoloa habonolo ho sebelisoa mekhoa ea ho buoa kapa ea bongaka. Ka linako tse ling u kanna oa hloka kalafo ho hang Nodular fasciitis (NF), proliferative fasciitis (PF), and proliferative myositis (PM) are pseudosarcomatous lesions that typically resolve spontaneously. We previously reported the feasibility of diagnosing this family of lesions by fine-needle aspiration cytology (FNAC) based on 17 cases
Nodular fasciitis is a self-limiting, pseudosarcomatous lesion composed of fibroblasts and myofibroblasts. 1 Although arising most often within the extremities, NF can often arise within the head and neck. Nodular fasciitis arises within fascia or subcutaneous tissue but can also occur within muscle or organ parenchyma, such as the parotid gland Abstract: Nodular fasciitis is a relatively rare, benign and proliferative lesion that is not typically found in the retroperitoneal (RP) space and has not been previously reported as a cause of gastric outlet obstruction (GOO). GOOs are frequently associated with malignancies, however, benign etiologies should be considered as well. We report the first case of GOO secondary to nodular.
Identification of Microorganisms on Cytology Specimens: A Review of Ancillary Diagnostic Techniques. Cancer Cytopathol. 2018;126: 643-653. 23) Allison DB, VandenBussche CJ, Rooper LM, Wakely PE, Rossi ED, Faquin WC, Ali SZ. Nodular Fasciitis of the Parotid Gland: A Challenging Diagnosis on Fine Needle Aspiration . Melanomas of the conjunctiva are rare. Adenocarcinomas of the gland of the third eyelid are uncommon nodular swellings in old dogs (mean age 11 years), and are rare in cats. Nodular fasciitis is the most prevalent primary disease of the sclera of dogs and occasionally occurs in cats